GR 55562 dihydrochloride, 5-HT1B / 5-HT1D receptor antagonist (ab120513)
Key features and details
- Selective 5-HT1B / 5-HT1D receptor antagonist
- CAS Number: 172854-55-6
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
GR 55562 dihydrochloride, 5-HT1B / 5-HT1D receptor antagonist -
Description
Selective 5-HT1B / 5-HT1D receptor antagonist -
Biological description
Selective, competitive 5-HT1B/ 5-HT1D receptor antagonist (pKi values are 7.4 and 6.2, respectively). Inhibits 5-HT evoked contraction in pulmonary resistance arteries (pEC10 = 7.26).
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Purity
> 99% -
CAS Number
172854-55-6 -
Chemical structure
Properties
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Chemical name
3-[3-(Dimethylamino)propyl]-4-hydroxy-N-[4-(4-pyridinyl)phenyl]benzamide dihydrochloride -
Molecular weight
448.39 -
Molecular formula
C23H25N3O2.2HCl -
PubChem identifier
56972159 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.Cl.CN(C)CCCc1cc(ccc1O)C(=O)Nc2ccc(cc2)c3ccncc3 -
Source
Synthetic
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Research areas