Gossypol, Proapoptotic agent; alters cell cycle and apoptosis proteins. (ab141050)
Key features and details
- Proapoptotic agent; alters cell cycle and apoptosis proteins.
- CAS Number: 303-45-7
- Purity: > 98%
- Soluble in DMSO to 25 mM and in ethanol to 25 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Gossypol, Proapoptotic agent; alters cell cycle and apoptosis proteins. -
Description
Proapoptotic agent; alters cell cycle and apoptosis proteins. -
Biological description
Proapoptotic agent derived from cottonseed. Exhibits a wide range of biological effects including anticancer and antifertility activity. Downregulates Bcl-2, p53 and various enzymes including caspases and dehydrogenases. -
Purity
> 98% -
CAS Number
303-45-7 -
Chemical structure
Properties
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Chemical name
1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-[2,2'-binaphthalene]-8,8'-dicarboxaldehyde -
Molecular weight
518.56 -
Molecular formula
C30H30O8 -
PubChem identifier
3503 -
Storage instructions
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in DMSO to 25 mM and in ethanol to 25 mM (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)c4c3cc(C)c(c1c(C)cc2c(c1O)c(c(O)c(O)c2C(C)C)C=O)c(O)c3c(C=O)c(O)c4O -
Source
Synthetic
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Research areas
