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Signal Transduction Protein Phosphorylation Tyrosine Kinases Receptor Tyrosine Kinases

Glipizide, Sulfonylurea receptor (ab142302)

Key features and details

  • Sulfonylurea receptor and ATP-sensitive K+ channel blocker
  • CAS Number: 29094-61-9
  • Purity: > 98%
  • Soluble in DMSO to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Glipizide, Sulfonylurea receptor
  • Description

    Sulfonylurea receptor and ATP-sensitive K+ channel blocker
  • Biological description

    Sulfonylurea receptor and ATP-sensitive K+ channel blocker. Highly potent insulinotropic agent (ED50 = 40 pM). Sulfonylurea and hypoglycemic agent. Active in vivo and in vitro. Orally active.
  • Purity

    > 98%
  • CAS Number

    29094-61-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    N-[2-[4-(Cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-5-methylpyrazine-2-carboxamide
  • Molecular weight

    445.54
  • Molecular formula

    C21H27N5O4S
  • PubChem identifier

    3478
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1=NC=C(N=C1)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
  • Source

    Synthetic

  • Research areas

    • Signal Transduction
    • Protein Phosphorylation
    • Tyrosine Kinases
    • Receptor Tyrosine Kinases
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Ion Channels
    • Potassium
    • Blockers
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Enzyme-Linked Receptors
    • Receptor tyrosine kinases
    • Insulin
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Kinase
    • Tyrosine Kinase
    • Receptor Tyrosine Kinase
    • Insulin

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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