G3335, PPARgamma antagonist. (ab142179)
Key features and details
- Selective, cell-permeable, reversible PPARγ antagonist.
- CAS Number: 36099-95-3
- Purity: > 97%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
G3335, PPARgamma antagonist. -
Description
Selective, cell-permeable, reversible PPARγ antagonist. -
Biological description
Selective, cell-permeable, reversible PPARγ antagonist (Kd = 8 μM). Inhibits activity of PPARγ agonist Rosiglitazone (ab120762). Active in vivo. -
Purity
> 97% -
CAS Number
36099-95-3 -
Chemical structure
Properties
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Chemical name
2-[[2-Amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid -
Molecular weight
333.34 -
Molecular formula
C16H19N3O5 -
PubChem identifier
3634442 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC=C2C(=C1)C(=CN2)CC(C(=O)NC(CCC(=O)O)C(=O)O)N -
Source
Synthetic
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Research areas
