FITC Anti-PD1 antibody [J43] (ab95791)
![FITC Anti-PD1 antibody [J43] (ab95791)](https://www.abcam.com/ps/products/95/ab95791/Images/ab95791-110033-anti-pd1-antibody-j43-fitc-flow-cytometry.gif "FITC Anti-PD1 antibody [J43] (ab95791)")
Key features and details
- FITC Armenian hamster monoclonal [J43] to PD1
- Suitable for: Flow Cyt
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG
Overview
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Product name
FITC Anti-PD1 antibody [J43]
See all PD1 primary antibodies -
Description
FITC Armenian hamster monoclonal [J43] to PD1 -
Host species
Armenian hamster -
Conjugation
FITC. Ex: 493nm, Em: 528nm -
Tested applications
Suitable for: Flow Cytmore details -
Immunogen
Syrian Hamster kidney cell line BKH transfected with Mouse PD1 cDNA
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Positive control
- Mouse Con-A activated spleen cell suspensions and Mouse PD-1 transfected cells.
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General notes
It is reported that J43 inhibits the binding of mouse PD-L1-Ig and mouse PD-L2-Ig to PD-1/BHK transfected cells. When administrated in vivo, both intact and Fab of J43 are reported to enhance contact hypersensitivity and exacerbate acute GVHD similar to transfer of PD-1-deficient cells. Injection of J43 also exacerbates EAE and NOD diabetes as do specific antibodies to mouse PD-L1 and PD-L2.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, PBS -
Concentration information loading... -
Purity
Protein G purified -
Primary antibody notes
It is reported that J43 inhibits the binding of mouse PD-L1-Ig and mouse PD-L2-Ig to PD-1/BHK transfected cells. When administrated in vivo, both intact and Fab of J43 are reported to enhance contact hypersensitivity and exacerbate acute GVHD similar to transfer of PD-1-deficient cells. Injection of J43 also exacerbates EAE and NOD diabetes as do specific antibodies to mouse PD-L1 and PD-L2. -
Clonality
Monoclonal -
Clone number
J43 -
Isotype
IgG -
Research areas
Images
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Flow Cytometry - FITC Anti-PD1 antibody [J43] (ab95791)Flow cytometry staining of ConA-stimulated splenocytes with Armenian Hamster IgG Isotype Control FITC (open histogram) and ab95791 (fillled histogram). Total viable cells were used for analysis.
