FAK Inhibitor 14, FAK autophosphorylation inhibitor (ab144503)
Key features and details
- FAK autophosphorylation inhibitor
- CAS Number: 4506-66-5
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
FAK Inhibitor 14, FAK autophosphorylation inhibitor -
Description
FAK autophosphorylation inhibitor -
Biological description
Selective focal adhesion kinase (FAK) autophosphorylation inhibitor (IC50 = 1 μM). No significant activity at other kinases including EGFR, PDGFR and IGF-RI. Increases cell detachment and inhibits cell adhesion in cancer cells. Anticancer agent. Active in vivo and in vitro.
Also available in simple stock solutions (ab146739) - add 1 ml of water to get an exact, ready-to-use concentration. -
CAS Number
4506-66-5 -
Chemical structure
Properties
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Chemical name
1,2,4,5-Benzenetetramine tetrahydrochloride -
Molecular weight
284.02 -
Molecular formula
C6H10N4.4HCl -
PubChem identifier
381091 -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.Cl.Cl.Cl.Nc1cc(N)c(N)cc1N -
Source
Synthetic