Erastin, ferrotopsis activator (ab209693)
Key features and details
- Selective ferrotopsis activator
- CAS Number: 571203-78-6
- Purity: > 98%
Soluble in DMSO to 20 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Erastin, ferrotopsis activator -
Description
Selective ferrotopsis activator -
Biological description
Selective ferrotopsis activator. Induces RAS-RAF-MEK-dependent non-apoptotic cell death via VDAC2 (IC50 = 0.1 μM).
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Purity
> 98% -
CAS Number
571203-78-6 -
Chemical structure
Properties
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Chemical name
2-[1-[4-[2-(4-Chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone
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Molecular weight
547.04 -
Molecular formula
C30H31ClN4O4 -
PubChem identifier
11214940 -
Storage instructions
Shipped at 4°C. Store at -20°C long term. It is important to note that this product is reported to be light sensitive. Store under desiccating conditions. -
Solubility overview
Soluble in DMSO to 20 mM
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Handling
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCOC1=CC=CC=C1N2C(=O)C3=CC=CC=C3N=C2C(C)N4CCN(CC4)C(=O)COC5=CC=C(C=C5)Cl -
Source
Synthetic
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Research areas