Efavirenz, reverse transcriptase inhibitor (ab146822)
Key features and details
- Non-nucleoside reverse transcriptase inhibitor
- CAS Number: 154598-52-4
- Purity: > 98%
- Soluble in DMSO to 5 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Efavirenz, reverse transcriptase inhibitor -
Description
Non-nucleoside reverse transcriptase inhibitor -
Alternative names
- EFV
- Sustiva
-
Biological description
Non-nucleoside reverse transcriptase inhibitor (NNRTI). Exhibits antiviral and anticancer activities. Clinically used to treat HIV type 1 infection. Prevents RNA plus-
strand initiation (IC50 = 17 nM). Induces autophagy and mitochondrial changes in neurons. Inhibits cellular proliferation and increases activation of p53 in various cancer cell lines. -
Purity
> 98% -
CAS Number
154598-52-4 -
Chemical structure
