Doxazosin mesylate, alpha1 adrenoceptor antagonist (ab120754)
Key features and details
- Selective α1 adrenoceptor antagonist
- CAS Number: 77883-43-3
- Purity: > 99%
- Soluble in DMSO to 75 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Doxazosin mesylate, alpha1 adrenoceptor antagonist -
Description
Selective α1 adrenoceptor antagonist -
Biological description
Selective α1 adrenoceptor antagonist (pKi values are 9.0, 8.5 and 8.4 at α1B, α1A and α1D receptors, respectively). Shows antihypertensive activity and induces apoptosis.
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Purity
> 99% -
CAS Number
77883-43-3 -
Chemical structure
Properties
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Chemical name
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazine methanesulfonate -
Molecular weight
547.58 -
Molecular formula
C23H25N5O5.CH3SO3H -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 75 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas