Dofetilide, hERG K+ channel blocker (ab141143)
Key features and details
- Antiarrhythmic agent. Potent and selective hERG K+ channel blocker
- CAS Number: 115256-11-6
- Purity: > 98%
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Dofetilide, hERG K+ channel blocker -
Description
Antiarrhythmic agent. Potent and selective hERG K+ channel blocker -
Biological description
Potent and selective hERG K+ channel blocker. Selectively blocks the rapid component of the delayed rectifier outward potassium current. Class III antiarrhythmic agent. Increases the atrial refractory period in vivo. Orally active. -
Purity
> 98% -
CAS Number
115256-11-6 -
Chemical structure
Properties
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Chemical name
1-(4-Methanesulfonamidophenoxy)-2-[N-(4-methanesulfonamidophenethyl)-N-methylamino]ethane -
Molecular weight
441.56 -
Molecular formula
C19H27N3O5S2 -
PubChem identifier
71329 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN(CCC1=CC=C(C=C1)NS(=O)(=O)C)CCOC2=CC=C(C=C2)NS(=O)(=O)C -
Source
Synthetic
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Research areas
