Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic acid, Anti-inflammatory agent (ab145212)
Key features and details
- Polyunsaturated fatty acid; anti-inflammatory agent
- CAS Number: 6217-54-5
- Purity: > 98%
- Soluble in ethanol
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic acid, Anti-inflammatory agent -
Description
Polyunsaturated fatty acid; anti-inflammatory agent -
Alternative names
- (4Z,7Z,10Z,13Z,16Z,19Z)-4,7,10,13,16,19-Docosahexaenoic acid
- 22:6(n-3)
- all-cis-docosa-4,7,10,13,16,19-hexa-enoic acid
see all -
Biological description
Abundant essential n-3 polyunsaturated fatty acid in the CNS, shown to play a major anti-inflammatory role. Prevents LPS-induced dendritic cell maturation, characterized by a lack of proinflammatory cytokine production. Improves the nitroso-redox balance and reduces VEGF-mediated angiogenic signaling in microvascular endothelial cells. Inhibits Aβ1-42 fibrillation and toxicity in vitro. Retinoid X receptor (RXR) ligand.
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Purity
> 98% -
CAS Number
6217-54-5 -
Chemical structure
Properties
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Molecular weight
328.50 -
Molecular formula
C22H32O2 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
