(-)-Cytisine, neuronal nicotinic agonist (ab120537)
Key features and details
- Potent, selective nAChR agonist
- CAS Number: 485-35-8
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
(-)-Cytisine, neuronal nicotinic agonist -
Description
Potent, selective nAChR agonist -
Biological description
Potent, selective agonist at neuronal nicotinic receptors. Acts as a partial agonist at β2-containing nicotinic receptors. (Ki values are 2 (α4β2), 5890 (α7), 480 (α3β4), 329 (α6/α4β4) and 492 nM (α1β1γδ)).
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Purity
> 99% -
CAS Number
485-35-8 -
Chemical structure
Properties
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Chemical name
(1R,5S)-1,2,3,4,5,6-hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one -
Molecular weight
190.24 -
Molecular formula
C11H14N2O -
PubChem identifier
22407 -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C2C=CC=C3C1CC(CNC1)CN23 -
Source
Synthetic
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Research areas
