CPI-613, alpha-ketoglutarate dehydrogenase inhibitor (ab143285)
Key features and details
- Tumor-selective α-ketoglutarate dehydrogenase inhibitor. Antitumor agent.
- CAS Number: 95809-78-2
- Purity: > 98%
- Soluble to 100 mM in DMSO and to 100 mM in ethanol
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
CPI-613, alpha-ketoglutarate dehydrogenase inhibitor -
Description
Tumor-selective α-ketoglutarate dehydrogenase inhibitor. Antitumor agent. -
Biological description
Tumor-selective α-ketoglutarate dehydrogenase inhibitor. Antitumor agent. Induces apoptotic and non-apoptotic cell death in tumor cell lines. Induces mitochondrial redox signal and loss of cell membrane potential. Lipoate analog. Shows potent antitumor effects in vivo. -
Purity
> 98% -
CAS Number
95809-78-2 -
Chemical structure
Properties
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Chemical name
6,8-Bis(benzylsulfanyl)octanoic acid -
Molecular weight
388.59 -
Molecular formula
C22H28O2S2 -
PubChem identifier
24770514 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble to 100 mM in DMSO and to 100 mM in ethanol -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
S(CCC(SCC1=CC=CC=C1)CCCCC(O)=O)CC2=CC=CC=C2 -
Source
Synthetic
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Research areas
