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Corynoline, Acetylcholinesterase (AChE) inhibitor (ab145575)

Key features and details

  • Acetylcholinesterase (AChE) inhibitor
  • CAS Number: 18797-79-0
  • Purity: > 98%
  • Form / State: Solid
  • Source: Corydalis sp.

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Overview

  • Product name

    Corynoline, Acetylcholinesterase (AChE) inhibitor
  • Description

    Acetylcholinesterase (AChE) inhibitor
  • Alternative names

    • (+)-Corynoline
    • 13-Methylchelidonine
  • Biological description

    Alkaloid compound isolated from Corydalis tubers. Anticancer activity. Exhibits cytotoxicity against several types of cancers in vitro, including lung carcinoma, colon carcinoma, melanoma, and ovarian carcinoma cell lines. Non-competitively inhibits acetylcholinesterase (AChE) in vitro (IC50 = 30.6 mM).

  • Purity

    > 98%
  • CAS Number

    18797-79-0
  • Chemical structure

    Chemical Structure

Properties

  • Molecular weight

    367.40
  • Molecular formula

    C21H21NO5
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC12C(CC3=CC4=C(C=C3C1N(CC5=C2C=CC6=C5OCO6)C)OCO4)O
  • Source

    Corydalis sp.

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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