Concanamycin A (Folimycin). Potent, selective vacuolar-type H+-ATPase inhibitor. (ab144227)
Key features and details
- Potent, selective vacuolar-type H+-ATPase inhibitor. Macrolide antibiotic agent.
- CAS Number: 80890-47-7
- Purity: > 98%
- Soluble in DMSO
- Form / State: Solid
- Source: Streptomyces sp.
Overview
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Product name
Concanamycin A (Folimycin). Potent, selective vacuolar-type H+-ATPase inhibitor. -
Description
Potent, selective vacuolar-type H+-ATPase inhibitor. Macrolide antibiotic agent. -
Alternative names
- Folimycin
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Biological description
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Purity
> 98% -
CAS Number
80890-47-7 -
Chemical structure
Properties
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Chemical name
(3Z,5E,7R,8R,9S,10S,11R,13E,15E,17S,18R)-18-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[[4-O-(Aminocarbonyl)-2,6-dideoxy-β-D-arabinohexopyranosyl]oxy]tetrahydro-2-hydroxy-5-methyl-6-(1E)-1-propen-1-yl-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-9-ethyl-8,10-dihydroxy-3,17-dimethoxy-5,7,11,13-tetramethyloxacyclooctadeca-3,5,13,15-tetraen-2-one -
Molecular weight
866.10 -
Molecular formula
C46H75NO14 -
PubChem identifier
6438151 -
Storage instructions
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in DMSO -
Handling
This product is supplied in one (or more) pack size which is freeze dried. Therefore the contents may not be readily visible, as they can coat the bottom or walls of the vial. Please see our FAQs and information page for more details on handling.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC[C@H]1[C@H]([C@@H](C/C(=C/C=C/[C@@H]([C@H](OC(=O)/C(=C/C(=C/[C@H]([C@H]1O)C)/C)/OC)[C@@H](C)[C@H]([C@H](C)[C@]2(C[C@H]([C@@H]([C@H](O2)/C=C/C)C)O[C@H]3C[C@H]([C@@H]([C@H](O3)C)OC(=O)N)O)O)O)OC)/C)C)O -
Source
Streptomyces sp.
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Research areas
