Cilostamide, PDE3 inhibitor (ab141273)
Key features and details
- Potent, selective PDE3 inhibitor
- CAS Number: 68550-75-4
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
Cilostamide, PDE3 inhibitor -
Description
Potent, selective PDE3 inhibitor -
Biological description
Potent, selective PDE3 inhibitor (IC50 values are 27 and 50 nM for PDE3A and PDE3B, respectively). Inhibits ADP-induced platelet aggregation (IC50 = 16.8 μM). Antithrombotic effects in vivo. Orally active.
-
Purity
> 98% -
CAS Number
68550-75-4 -
Chemical structure
Properties
-
Chemical name
N-Cyclohexyl-4-[(1,2-dihydro-2-oxo-6-quinolinyl)oxy]-N-methylbutanamide -
Molecular weight
342.44 -
Molecular formula
C20H26N2O3 -
PubChem identifier
2753 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
CN(C1CCCCC1)C(=O)CCCOc2ccc3NC(=O)C=Cc3c2 -
Source
Synthetic
-
Research areas