CI 976 (PD 128042) (ab145965)
Key features and details
- Potent, selective ACAT inhibitor
- CAS Number: 114289-47-3
- Purity: > 98%
- Soluble in ethanol to 50 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
CI 976 (PD 128042) -
Description
Potent, selective ACAT inhibitor -
Alternative names
- PD 128042
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Biological description
Potent, selective ACAT inhibitor (IC50 = 73 nM). Lowers non-HDL and increases HDL-cholesterol concentrations. Shows antidyslipidemic effects in vivo. Orally active.
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Purity
> 98% -
CAS Number
114289-47-3 -
Chemical structure
Properties
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Chemical name
2,2-Dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide -
Molecular weight
393.57 -
Molecular formula
C23H39NO4 -
PubChem identifier
122327 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 50 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCCCCCCCCC(C)(C)C(=O)NC1=C(C=C(C=C1OC)OC)OC -
Source
Synthetic
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Research areas