CHM1, Antitumor agent (ab141225)
Key features and details
- Potent antitumor agent
- CAS Number: 154554-41-3
- Purity: > 99%
- Soluble in DMSO to 5 mM (with warming) and in ethanol to 5 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
CHM1, Antitumor agent -
Description
Potent antitumor agent -
Biological description
Potent antitumor agent. Antiproliferative, anti-angiogenic and anti-apoptotic in a dose dependent manner. Reduces cell viability (IC50 = 0.13 - 8.2 μM) and tumor invasion. Active in vitro and in vivo. Increases expression of DR5, TRIAL, p53. Reduces tumor polymerisation and caspase activation.
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Purity
> 99% -
CAS Number
154554-41-3 -
Chemical structure
Properties
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Chemical name
6-(2-Fluorophenyl)-1,3-dioxolo[4,5-g]quinolin-8(5H)-one -
Molecular weight
283.26 -
Molecular formula
C16H10FNO3 -
PubChem identifier
375860 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 5 mM (with warming) and in ethanol to 5 mM (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Fc4ccccc4C=2Nc1cc3OCOc3cc1C(=O)C=2 -
Source
Synthetic
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Research areas
