Chetomin, HIF signaling inhibitor (ab144222)
Key features and details
- Potent HIF signaling inhibitor
- CAS Number: 1403-36-7
- Purity: > 98%
- Soluble in DMSO
- Form / State: Solid
- Source: Chaetomium sp.
Overview
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Product name
Chetomin, HIF signaling inhibitor -
Description
Potent HIF signaling inhibitor -
Biological description
Potent HIF signaling inhibitor. Reduces CA9 and VEGF expression in hypoxic cells (IC50 = 10 nM, secreted VEGF, Hep38 cells). Shows antibacterial and antifungal effects. Shows antitumor effects in vivo. -
Purity
> 98% -
CAS Number
1403-36-7 -
Chemical structure
Properties
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Molecular weight
710.87 -
Molecular formula
C31H30N6O6S4 -
PubChem identifier
10417379 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN1C(=O)[C@]2(N(C(=O)[C@@]1(SS2)CC3=CN(C4=CC=CC=C43)[C@]56C[C@]78C(=O)N([C@](C(=O)N7[C@H]5NC9=CC=CC=C69)(SS8)CO)C)C)CO -
Source
Chaetomium sp.
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Research areas