CHAPS, Zwitterionic non-denaturing detergent (ab141396)
Key features and details
- Zwitterionic non-denaturing detergent for solubilizing membrane proteins
- CAS Number: 75621-03-3
- Purity: > 98%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
CHAPS, Zwitterionic non-denaturing detergent -
Description
Zwitterionic non-denaturing detergent for solubilizing membrane proteins -
Alternative names
- 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulphonate
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Biological description
Zwitterionic non-denaturing detergent that protects the native state of proteins, able to disrupt non-specific protein interactions and has less protein aggregation than non-ionic detergents. It is electrically neutral and easily removed by dialysis. Often used in the solubilization and purification of membrane proteins.
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Purity
> 98% -
CAS Number
75621-03-3 -
Chemical structure
Properties
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Chemical name
3-[Dimethyl-[3-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azaniumyl]propane-1-sulfonate -
Molecular weight
614.90 -
Molecular formula
C32H58N2O7S -
PubChem identifier
107670 -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C -
Source
Synthetic
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Research areas
