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CHAPS, Zwitterionic non-denaturing detergent (ab141396)

Key features and details

  • Zwitterionic non-denaturing detergent for solubilizing membrane proteins
  • CAS Number: 75621-03-3
  • Purity: > 98%
  • Soluble in water to 100 mM
  • Form / State: Solid
  • Source: Synthetic

Overview

  • Product name

    CHAPS, Zwitterionic non-denaturing detergent

  • Description

    Zwitterionic non-denaturing detergent for solubilizing membrane proteins

  • Alternative names

    • 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulphonate

  • Biological description

    Zwitterionic non-denaturing detergent that protects the native state of proteins, able to disrupt non-specific protein interactions and has less protein aggregation than non-ionic detergents. It is electrically neutral and easily removed by dialysis. Often used in the solubilization and purification of membrane proteins.

  • Purity

    > 98%

  • CAS Number

    75621-03-3

  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    3-[Dimethyl-[3-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azaniumyl]propane-1-sulfonate

  • Molecular weight

    614.90

  • Molecular formula

    C32H58N2O7S

  • PubChem identifier

    107670

  • Storage instructions

    Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.

  • Solubility overview

    Soluble in water to 100 mM

  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C

  • Source

    Synthetic

  • Research areas

Images

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