Celastrol from Celastrus scandens, Anti-inflammatory and antiproliferative agent (ab120655)
Key features and details
- Anti-inflammatory and antiproliferative agent
- CAS Number: 34157-83-0
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 25 mM
- Form / State: Solid
- Source: Celastrus scandens
Overview
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Product name
Celastrol from Celastrus scandens, Anti-inflammatory and antiproliferative agent -
Description
Anti-inflammatory and antiproliferative agent -
Alternative names
- Tripterine
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Biological description
Anti-inflammatory and antiproliferative effects (IC50 = 2.12 µM). Able to modulate multiple cell-signaling pathways (inhibits NF-κB, upregulates cytoplasmic HSP70 and HSP27, suppress VEGF/Akt/mTOR pathways and inhibits TNF-α, proteasome inhibitor).
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Purity
> 99% -
CAS Number
34157-83-0 -
Chemical structure