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Signal Transduction Metabolism Lipid metabolism

CDC, lipoxygenase inhibitor (ab141560)

Key features and details

  • Potent, selective lipoxygenase inhibitor
  • CAS Number: 132465-11-3
  • Purity: > 98%
  • Soluble in DMSO to 10 mM and in ethanol to 10 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    CDC, lipoxygenase inhibitor
  • Description

    Potent, selective lipoxygenase inhibitor
  • Biological description

    Potent, selective 12-Lipoxygenase (12-LO) inhibitor (IC50 = 63 nM). Also inhibits 15-LO and 5-LO (IC50 values are 3.33 and 1.89 μM respectively). Active in vivo.
  • Purity

    > 98%
  • CAS Number

    132465-11-3
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    Cinnamyl-3,4-dihydroxy-α-cyanocinnamate
  • Molecular weight

    321.30
  • Molecular formula

    C19H15NO4
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 10 mM and in ethanol to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    N#C\C(=C\c1cc(O)c(O)cc1)C(=O)OC\C=C\c2ccccc2
  • Source

    Synthetic

  • Research areas

    • Signal Transduction
    • Metabolism
    • Lipid metabolism
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Oxygenase
    • Lipooxygenase
    • Inhibitors

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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