CCT128930 (ab273533)
Key features and details
- Potent and selective AKT2 inhibitor
- CAS Number: 885499-61-6
- Purity: = 98%
Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
CCT128930 -
Description
Potent and selective AKT2 inhibitor -
Biological description
Potent and selective AKT2 inhibitor (IC50= 6 nM) with selectivity greater than 28-fold and 20-fold over PKA kinase (IC50= 168 nM) and p70S6K (IC50= 120 nM), respectively.
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Purity
= 98% -
General notes
For obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while.
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CAS Number
885499-61-6 -
Chemical structure
Properties
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Chemical name
4-[(4-Chlorophenyl)methyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4-piperidinamine
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Molecular weight
341.84 -
Molecular formula
C18H20ClN5 -
PubChem identifier
17751819 -
Storage instructions
Shipped at 4°C. Store at -20°C. Please see notes section. -
Solubility overview
Soluble in DMSO to 50 mM
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Handling
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1CN(CCC1(CC2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4 -
Source
Synthetic