Carmofur, Antimetabolite agent (ab142653)
Key features and details
- Potent acid ceramidase inhibitor. Antimetabolite agent.
- CAS Number: 61422-45-5
- Purity: > 97%
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Carmofur, Antimetabolite agent -
Description
Potent acid ceramidase inhibitor. Antimetabolite agent. -
Biological description
Potent acid ceramidase inhibitor (IC50 = 29 nM). Antimetabolite agent. cytostatic pyrimidine analogue derivative of fluorouracil (Asc 2387) . Shows antitumor effects in vivo. Orally active. -
Purity
> 97% -
CAS Number
61422-45-5 -
Chemical structure
Properties
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Chemical name
5-Fluoro-N-hexyl-2,4-dioxopyrimidine-1-carboxamide -
Molecular weight
257.26 -
Molecular formula
C11H16FN3O3 -
PubChem identifier
2577 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCCCCNC(=O)N1C=C(C(=O)NC1=O)F -
Source
Synthetic
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Research areas
