Calciseptine (Recombinant), L-type Ca2+ channel blocker (ab141856)
Key features and details
- Potent, specific L-type Ca2+ channel blocker
- CAS Number: 178805-91-9
- Purity: > 98%
- Soluble in water
- Form / State: Solid
- Source: Dendroaspis polylepis polylepis
Overview
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Product name
Calciseptine (Recombinant), L-type Ca2+ channel blocker -
Description
Potent, specific L-type Ca2+ channel blocker -
Biological description
Potent, specific L-type Ca2+ channel blocker (IC50 = 15 nM). Inactive on other voltage-dependent Ca2+ channels. Smooth muscle relaxant and cardiacontraction inhibitor. Neurotoxic. Active in vivo and in vitro. -
Purity
> 98% -
CAS Number
178805-91-9 -
Chemical structure
Properties
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Molecular weight
7167.40 -
Molecular formula
C304H477N91O88S11 -
Sequence
MRICYIHKASLPRATKTCVENTCYKMFIRTQREYISERGCGCPTAMWPYQTECCKGDRCNK (Modifications: Disulfide bonds: 4-23, 18-40, 42-53, 54-59) -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Dendroaspis polylepis polylepis
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Research areas