Bumetanide, Na+/2Cl-/K+ cotransporter inhibitor (ab142489)
Key features and details
- Potent, selective Na+/2Cl-/K+ cotransporter inhibitor
- CAS Number: 28395-03-1
- Purity: > 98%
- Soluble in DMSO to 50 mM and in ethanol to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Bumetanide, Na+/2Cl-/K+ cotransporter inhibitor -
Description
Potent, selective Na+/2Cl-/K+ cotransporter inhibitor -
Biological description
Potent, selective Na+/2Cl-/K+ cotransporter inhibitor. Shows 40-fold greater potency than furosemide (Asc 314). Shows diuretic and anticonvulsant effects in vivo. Orally active. -
Purity
> 98% -
CAS Number
28395-03-1 -
Chemical structure
Properties
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Chemical name
3-(Butylamino)-4-phenoxy-5-sulfamoylbenzoic acid -
Molecular weight
364.42 -
Molecular formula
C17H20N2O5S -
PubChem identifier
2471 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM and in ethanol to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2 -
Source
Synthetic
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Research areas
