BMS 345541, IKK-2 and IKK-1 inhibitor (ab144822)
Key features and details
- Highly selective cell permeable IKK-2 and IKK-1 inhibitor
- CAS Number: 445430-58-0
- Purity: > 99%
Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
BMS 345541, IKK-2 and IKK-1 inhibitor -
Description
Highly selective cell permeable IKK-2 and IKK-1 inhibitor -
Biological description
Highly selective cell permeable IKK-2 and IKK-1 inhibitor (IC50 values are 0.3 and 4 μM for IKK-2 and IKK-1 respectively). Blocks NF-κB-dependent transcription. Shows anti-inflammatory and radiosensitizing effects in vivo. Orally active. -
Purity
> 99% -
CAS Number
445430-58-0 -
Chemical structure
Properties
-
Chemical name
N'-(1,8-Dimethylimidazo[1,2-a]quinoxalin-4-yl)ethane-1,2-diamine
-
Molecular weight
255.32 -
Molecular formula
C14H17N5 -
PubChem identifier
9813758 -
Storage instructions
Store at +4°C (desiccating conditions). -
Solubility overview
Soluble in DMSO to 25 mM
-
Handling
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
CC1=CC2=C(C=C1)N=C(C3=NC=C(N23)C)NCCN -
Source
Synthetic
-
Research areas
