BML 284, Wnt signaling activator (ab145241)
Key features and details
- Cell-permeable Wnt signaling activator
- CAS Number: 853220-52-7
- Purity: > 98%
- Soluble in ethanol to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
BML 284, Wnt signaling activator -
Description
Cell-permeable Wnt signaling activator -
Biological description
Cell-permeable Wnt signaling activator. Induces β-catenin and TCF-dependent transcriptional activity (EC50 = 0.7 μM). Activates Wnt without inhibiting GSK-3β.Shows developmental effects in vivo. -
Purity
> 98% -
CAS Number
853220-52-7 -
Chemical structure
Properties
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Chemical name
4-N-(1,3-Benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine -
Molecular weight
350.40 -
Molecular formula
C19H18N4O3 -
PubChem identifier
11210285 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 100 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
COC1=CC=CC(=C1)C2=CC(=NC(=N2)N)NCC3=CC4=C(C=C3)OCO4 -
Source
Synthetic
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Research areas
