BML-244, Cathepsin K inhibitor (ab141723)
Key features and details
- Potent cathepsin K inhibitor
- CAS Number: 104062-70-6
- Purity: > 98%
- Soluble in DMSO to 25 mM and in ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
BML-244, Cathepsin K inhibitor -
Description
Potent cathepsin K inhibitor -
Biological description
Highly potent, cell-permeable inhibitor of cathepsin K (IC50 = 51 nM). Cell permeable and orally active. -
Purity
> 98% -
CAS Number
104062-70-6 -
Chemical structure
Properties
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Chemical name
tert-Butyl N-[(2S)-1-oxohexan-2-yl]carbamate -
Molecular weight
215.30 -
Molecular formula
C11H21NO3 -
PubChem identifier
10420833 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM and in ethanol to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCCC(C=O)NC(=O)OC(C)(C)C -
Source
Synthetic
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Research areas