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Signal Transduction Cytoskeleton / ECM Extracellular Matrix

BML-244, Cathepsin K inhibitor (ab141723)

Key features and details

  • Potent cathepsin K inhibitor
  • CAS Number: 104062-70-6
  • Purity: > 98%
  • Soluble in DMSO to 25 mM and in ethanol to 50 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    BML-244, Cathepsin K inhibitor
  • Description

    Potent cathepsin K inhibitor
  • Biological description

    Highly potent, cell-permeable inhibitor of cathepsin K (IC50 = 51 nM). Cell permeable and orally active.
  • Purity

    > 98%
  • CAS Number

    104062-70-6
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    tert-Butyl N-[(2S)-1-oxohexan-2-yl]carbamate
  • Molecular weight

    215.30
  • Molecular formula

    C11H21NO3
  • PubChem identifier

    10420833
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 25 mM and in ethanol to 50 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCC(C=O)NC(=O)OC(C)(C)C
  • Source

    Synthetic

  • Research areas

    • Cardiovascular
    • Angiogenesis
    • Adhesion / ECM
    • Extracellular Matrix
    • Neuroscience
    • Cell Adhesion Proteins
    • Proteases
    • Signal Transduction
    • Cytoskeleton / ECM
    • Extracellular Matrix
    • ECM Enzymes
    • Other Enzymes
    • Cancer
    • Invasion/microenvironment
    • ECM
    • Extracellular matrix
    • Other
    • Cell Biology
    • Proteolysis / Ubiquitin
    • Proteolytic enzymes
    • Cysteine protease
    • Cathepsins
    • Cardiovascular
    • Atherosclerosis
    • Thrombosis
    • Other
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Protease
    • Cathepsin
    • Inhibitors

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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