(-)-Bicuculline methiodide (mM/ml), GABAA antagonist (ab144491)
Key features and details
- GABAA antagonist. 1 ml water soluble pack.
- CAS Number: 40709-69-1
- Purity: > 99%
- Soluble in 1 ml water to give specified mM/ml concentration
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
(-)-Bicuculline methiodide (mM/ml), GABAA antagonist -
Description
GABAA antagonist. 1 ml water soluble pack. -
Biological description
Water-soluble GABAA antagonist. Methiodide salt of (+)-bicuculline (ab120107). Actions on neuronal Ca2+-activated K+ channels reported.
Soluble in 1 ml water to give specified mM/ml concentration. -
Purity
> 99% -
CAS Number
40709-69-1 -
Chemical structure
Properties
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Chemical name
[S-(R*,S*)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium iodide -
Molecular weight
509.29 -
Molecular formula
C21H20INO6 -
PubChem identifier
185826 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in 1 ml water to give specified mM/ml concentration -
Handling
This product is supplied in one (or more) pack size which is freeze dried. Therefore the contents may not be readily visible, as they can coat the bottom or walls of the vial. Please see our FAQs and information page for more details on handling.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
[I-].C[N+]5(C)CCc1cc6OCOc6cc1[C@@H]5[C@H]4OC(=O)c3c4ccc2OCOc23 -
Source
Synthetic
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Research areas
