Bexarotene, RXR agonist (ab141025)
Key features and details
- Potent RXR agonist
- CAS Number: 153559-49-0
- Purity: > 99%
- Soluble in ethanol to 25 mM and in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Bexarotene, RXR agonist -
Description
Potent RXR agonist -
Biological description
Potent RXR agonist (Ki values are 30.5, 16.4, 19.7, >1000 for RXRα, RXRβ, RXRγ and RAR respectively). Inhibits neurodegeneration and displays anticancer activity in vivo and in vitro. Blood-brain barrier permeable.
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Purity
> 99% -
CAS Number
153559-49-0 -
Chemical structure
Properties
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Chemical name
4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-
naphthalenyl)ethenyl]benzoic acid -
Molecular weight
348.48 -
Molecular formula
C24H28O2 -
Storage instructions
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in ethanol to 25 mM and in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(O)c1ccc(cc1)C(=C)c2cc3c(cc2C)C(C)(C)CCC3(C)C -
Source
Synthetic
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Research areas
