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Epigenetics and Nuclear Signaling Transcription Domain Families Developmental Families HOX

Anti-TLX1 antibody (ab105496)

Price and availability

274 732 ₸

Availability

Order now and get it on Thursday February 25, 2021

Anti-TLX1 antibody (ab105496)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Rabbit polyclonal to TLX1
  • Suitable for: WB
  • Reacts with: Mouse
  • Isotype: IgG

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Overview

  • Product name

    Anti-TLX1 antibody
    See all TLX1 primary antibodies
  • Description

    Rabbit polyclonal to TLX1
  • Host species

    Rabbit
  • Tested Applications & Species

    Application Species
    WB
    Mouse
    See all applications and species data
  • Immunogen

    Synthetic peptide corresponding to Mouse TLX1 aa 1-100 conjugated to keyhole limpet haemocyanin.
    (Peptide available as ab125503)

  • Positive control

    • This antibody gave a positive signal in Mouse Hippocampus tissue lysate.
  • General notes

     This product was previously labelled as HOX11

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituent: PBS

    Batches of this product that have a concentration
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Epigenetics and Nuclear Signaling
    • Transcription
    • Domain Families
    • Developmental Families
    • HOX
    • Developmental Biology
    • Organogenesis
    • Excretory system development
    • Kidney development

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab105496 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Guaranteed

Tested applications are guaranteed to work and covered by our Abpromise guarantee.

Predicted

Predicted to work for this combination of applications and species but not guaranteed.

Incompatible

Does not work for this combination of applications and species.

Application Species
WB
Mouse
Application Abreviews Notes
WB
Use a concentration of 1 µg/ml. Detects a band of approximately 35 kDa (predicted molecular weight: 35 kDa).
Notes
WB
Use a concentration of 1 µg/ml. Detects a band of approximately 35 kDa (predicted molecular weight: 35 kDa).

Target

  • Function

    Controls the genesis of the spleen. Binds to the DNA sequence 5'-GGCGGTAAGTGG-3'.
  • Involvement in disease

    Note=A chromosomal aberration involving TLX1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(10;14)(q24;q11) with TCRD.
  • Sequence similarities

    Contains 1 homeobox DNA-binding domain.
  • Cellular localization

    Nucleus.
  • Target information above from: UniProt accession P31314 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 21908 Mouse
    • SwissProt: P43345 Mouse
    • Unigene: 391203 Mouse
    • Alternative names

      • Homeo box 11 (T cell leukemia 3 associated breakpoint homologous to Drosophila Notch) antibody
      • Homeo box 11 (T cell lymphoma 3 associated breakpoint) antibody
      • Homeobox 11 antibody
      • Homeobox protein Hox 11 antibody
      • Homeobox protein Hox-11 antibody
      • Homeobox TLX-1 antibody
      • Hox-11 antibody
      • Hox11 antibody
      • MGC163402 antibody
      • OTTHUMP00000020816 antibody
      • Proto oncogene TCL 3 antibody
      • Proto-oncogene TCL-3 antibody
      • RGD1563655 antibody
      • T cell leukemia homeobox protein 1 antibody
      • T cell leukemia lymphoma protein 3 antibody
      • T-all, included antibody
      • T-cell acute lymphocytic leukemia, included antibody
      • T-cell leukemia 3 gene antibody
      • T-cell leukemia homeobox protein 1 antibody
      • T-cell leukemia, homeobox 1 antibody
      • T-cell leukemia/lymphoma protein 3 antibody
      • TCL 3 proto oncogene antibody
      • TCL3 antibody
      • Tlx-1 antibody
      • TLX1 antibody
      • TLX1_HUMAN antibody
      see all

    Images

    • Western blot - Anti-TLX1 antibody (ab105496)
      Western blot - Anti-TLX1 antibody (ab105496)
      Anti-TLX1 antibody (ab105496) at 1 µg/ml + Mouse Hippocampus Tissue Lysate at 10 µg

      Secondary
      Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution

      Developed using the ECL technique.

      Performed under reducing conditions.

      Predicted band size: 35 kDa
      Observed band size: 35 kDa
      Additional bands at: 85 kDa. We are unsure as to the identity of these extra bands.


      Exposure time: 1 minute

    Protocols

    • Western blot protocols

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab105496? Please let us know so that we can cite the reference in this datasheet.

    ab105496 has not yet been referenced specifically in any publications.

    Images

    • Western blot - Anti-TLX1 antibody (ab105496)
      Western blot - Anti-TLX1 antibody (ab105496)
      Anti-TLX1 antibody (ab105496) at 1 µg/ml + Mouse Hippocampus Tissue Lysate at 10 µg

      Secondary
      Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution

      Developed using the ECL technique.

      Performed under reducing conditions.

      Predicted band size: 35 kDa
      Observed band size: 35 kDa
      Additional bands at: 85 kDa. We are unsure as to the identity of these extra bands.


      Exposure time: 1 minute

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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