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Immunology Adaptive Immunity T Cells Non-CD

Anti-TCR alpha + TCR beta antibody [H57-597] (ab25336)

Key features and details

  • Armenian hamster monoclonal [H57-597] to TCR alpha + TCR beta
  • Reacts with: Mouse
  • Isotype: IgG

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Overview

  • Product name

    Anti-TCR alpha + TCR beta antibody [H57-597]
    See all TCR alpha + TCR beta primary antibodies
  • Description

    Armenian hamster monoclonal [H57-597] to TCR alpha + TCR beta
  • Host species

    Armenian hamster
  • Specificity

    ab25336 reacts with a common epitope of the ß chain of the mouse aß T cell receptor (TCR) complex.
  • Species reactivity

    Reacts with: Mouse
  • Immunogen

    TCR affinity purified from T-cell hybridoma DO-11.10 (Mouse)

  • General notes

    ab25336 does not react with yd TCR-bearing cells. Plate-bound or soluble ab25336 activates aß TCR-bearing T cells. In vitro and in vivo, ab25336 can induce immature thymocytes to undergo apoptosis. In vivo administration of ab25336 has been shown to deplete aß TCR-bearing cells to near completion and prevent graft rejection.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    pH: 7.20
    Preservative: 0.09% Sodium azide
    Constituents: 0.87% Sodium chloride, 0.14% Monobasic dihydrogen sodium phosphate
  • Concentration information loading...
  • Purity

    Affinity purified
  • Purification notes

    Purified from tissue culture supernatant
  • Primary antibody notes

    ab25336 does not react with yd TCR-bearing cells. Plate-bound or soluble ab25336 activates aß TCR-bearing T cells. In vitro and in vivo, ab25336 can induce immature thymocytes to undergo apoptosis. In vivo administration of ab25336 has been shown to deplete aß TCR-bearing cells to near completion and prevent graft rejection.
  • Clonality

    Monoclonal
  • Clone number

    H57-597
  • Isotype

    IgG
  • Research areas

    • Immunology
    • Adaptive Immunity
    • T Cells
    • Non-CD

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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