Anti-NCOR2/SMRT antibody [1212]
See all NCOR2/SMRT primary antibodies

Mouse monoclonal [1212] to NCOR2/SMRT

Mouse

We have data to indicate that this antibody may not cross react with Rat. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues.

Reacts with: Human
Predicted to work with: Mouse

Synthetic peptide corresponding to Human NCOR2/SMRT.
Sequence:

CGGA-SASDPHREKTQ

(Peptide available as ab4909)

Run BLAST with Run BLAST with

Liquid

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 99% PBS

Affinity purified

Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand-dependent nuclear receptor superfamily. Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcription activity of the nuclear receptor with which they associate. Silencing Mediator of Retinoic acid and Thyroid hormone receptor (SMRT) and nuclear receptor corepressor (N-CoR) are related transcriptional corepressors which contain two distinct domains capable of interacting with unliganded nuclear receptors to repress their basal transcriptional activity.

Monoclonal

1212

IgG1

• Epigenetics and Nuclear Signaling
• Chromatin Modifying Enzymes
• Acetylation

• Signal Transduction
• Signaling Pathway
• Nuclear Signaling
• Nuclear Hormone Receptors
• Co-activators/co-repressors

• Epigenetics and Nuclear Signaling
• Nuclear Signaling Pathways
• Nuclear Receptors
• Co-activators/co-repressors

• Epigenetics and Nuclear Signaling
• Transcription
• Co-factors

• Epigenetics and Nuclear Signaling
• Chromatin Modifying Enzymes
• Acetylation
• HDACs
• Class II / Hda1 Class

• Cancer
• Cancer Metabolism
• Metabolic signaling pathway
• Metabolism of lipids and lipoproteins

• Metabolism
• Pathways and Processes
• Metabolic signaling pathways
• Lipid and lipoprotein metabolism
• Lipid metabolism

• Metabolism
• Pathways and Processes
• Cofactors, Vitamins / minerals
• Co-factors

• Metabolism
• Types of disease
• Cancer