Anti-Macrophages + Monocytes antibody [ER-HR3] (ab59697)
Key features and details
- Rat monoclonal [ER-HR3] to Macrophages + Monocytes
- Reacts with: Mouse
- Isotype: IgG2c
Overview
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Product name
Anti-Macrophages + Monocytes antibody [ER-HR3] -
Description
Rat monoclonal [ER-HR3] to Macrophages + Monocytes -
Host species
Rat -
Specificity
This antibody is reactive to the majority of mouse monocytes and a subset of mature resident macrophages, especially those located in hemopoietic organs. Whereas all other leukocytes are negative, up to 70% of circulating monocytes stain positive with this antibody. About 30% of bone marrow cells express the antigen. Other positive macrophages can be found in the splenic red pulp, in the mesentric lymphoid paracortex, interfollicular areas of Peyer's patches and bone marrow. Few positive cells are observed in the thymic cortex and the connective tissues of the gastro-intestinal tract, the dermis and the renal medulla. Epidermal Langerhans cells also express the antigen. -
Species reactivity
Reacts with: Mouse -
Immunogen
Tissue/ cell preparation
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General notes
This antibody can be used to identify and localize a very distinct macrophage subpopulation found in various mouse organs and its distribution pattern is unique compared to that from other macrophage-specific antibodies. The antibody is especially suitable for ontogenic studies because ER-HR3 positive macrophages are closely related to hemopoietic islands, especially at erythropoietic sites.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.1% BSA -
Concentration information loading... -
Purity
Protein G purified -
Purification notes
Purified antibody in 0.2µm filtered solution. -
Primary antibody notes
This antibody can be used to identify and localize a very distinct macrophage subpopulation found in various mouse organs and its distribution pattern is unique compared to that from other macrophage-specific antibodies. The antibody is especially suitable for ontogenic studies because ER-HR3 positive macrophages are closely related to hemopoietic islands, especially at erythropoietic sites. -
Clonality
Monoclonal -
Clone number
ER-HR3 -
Isotype
IgG2c -
Research areas