Anti-IL-6R antibody [rhPM-1 (Tocilizumab)] (ab275982)
![Anti-IL-6R antibody [rhPM-1 (Tocilizumab)] (ab275982)](https://www.abcam.com/ps/products/275/ab275982/Images/ab275982-411988-anti-IL6receptor-antibody-ICCIF.jpg "Anti-IL-6R antibody [rhPM-1 (Tocilizumab)] (ab275982)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [rhPM-1 (Tocilizumab)] to IL-6R
- Suitable for: ICC/IF
- Reacts with: Human
Overview
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Product name
Anti-IL-6R antibody [rhPM-1 (Tocilizumab)]
See all IL-6R primary antibodies -
Description
Rabbit monoclonal [rhPM-1 (Tocilizumab)] to IL-6R -
Host species
Rabbit -
Tested Applications & Species
See all applications and species dataApplication Species ICC/IF Human
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Immunogen
Recombinant fragment corresponding to Human IL-6R. This antibody was prepared by CDR grafting of mouse AUK 12-20 antibody onto a human framework regions.
Database link: A0N0L5 -
Positive control
- ICC: U937 cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.
One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.
Learn more here.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.02% Proclin 300
Constituent: 99.98% PBS -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
rhPM-1 (Tocilizumab) -
Isotype
IgG -
Light chain type
kappa -
Research areas
Images
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Immunocytochemistry/ Immunofluorescence - Anti-IL-6R antibody [rhPM-1 (Tocilizumab)] (ab275982)
Immunofluorescence analysis of paraformaldehyde fixed U937 (human histiocytic lymphoma cell line) cells on Shi-fix coverslips, permeabilized with 0.15% Triton and labeled with ab275982 at 10 µg/ml for 1h followed by Alexa Fluor®488 secondary antibody (1 µg/ml) (Green), showing membrane staining. The nuclear stain is DAPI (blue). Panels show from left-right, top-bottom ab275982, DAPI, merged channels and an isotype control. The isotype control was stained with an anti-Fluorescein antibody followed by Alexa Fluor®488 secondary antibody.
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![Anti-IL-6R antibody [rhPM-1 (Tocilizumab)] (ab275982)](https://www.abcam.com/ps/products/275/ab275982/Images/ab275982-2-benefits-of-recombinant-antibodies.png)
Anti-IL-6R antibody [rhPM-1 (Tocilizumab)] (ab275982)