Anti-IL-21R antibody (ab5980)
Key features and details
- Rabbit polyclonal to IL-21R
- Suitable for: ICC/IF, IHC-P, WB
- Reacts with: Rat, Human
- Isotype: IgG
Overview
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Product name
Anti-IL-21R antibody
See all IL-21R primary antibodies -
Description
Rabbit polyclonal to IL-21R -
Host species
Rabbit -
Tested applications
Suitable for: ICC/IF, IHC-P, WBmore details -
Species reactivity
Reacts with: Rat, Human -
Immunogen
Synthetic peptide corresponding to Human IL-21R aa 97-111.
Sequence:NITDQSGNYSQECGS
(Peptide available asab6225) -
Positive control
- WB: HepG2 cell lysate. IHC-P: Rat lung tissue. ICC/IF: A431 cells.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Primary antibody notes
A novel cytokine related to IL-2 and IL-15 was recently identified and designated IL-21. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling. Both IL-21R and the gc are necessary for IL-21 function. IL-21 and its receptor activate the JAK-STAT signaling pathway. IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Images
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Western blot - Anti-IL-21R antibody (ab5980)Lane 1 : Anti-IL-21R antibody (ab5980) at 1 µg/ml
Lane 2 : Anti-IL-21R antibody (ab5980) at 2 µg/ml
All lanes : HepG2 cell lysate
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-21R antibody (ab5980)ab5980 at 10µg/ml staining IL-21R in rat lung by IHC.
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Immunocytochemistry/ Immunofluorescence - Anti-IL-21R antibody (ab5980)Immunocytochemistry/Immunofluorescence labelling A431 cells with ab5980 at 20µg/ml.
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Immunocytochemistry/ Immunofluorescence - Anti-IL-21R antibody (ab5980)Immunofluorescence of IL-21 Receptor in Rat Lung cells using ab5980 at 20 ug/ml.