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Signal Transduction Metabolism Energy Metabolism

Anti-GCKR antibody (ab87739)

Price and availability

264 681 ₸

Availability

Order now and get it on Tuesday March 09, 2021

Anti-GCKR antibody (ab87739)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Rabbit polyclonal to GCKR
  • Suitable for: WB
  • Reacts with: Human
  • Isotype: IgG

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Overview

  • Product name

    Anti-GCKR antibody
    See all GCKR primary antibodies
  • Description

    Rabbit polyclonal to GCKR
  • Host species

    Rabbit
  • Tested Applications & Species

    Application Species
    WB
    Human
    See all applications and species data
  • Immunogen

    Synthetic peptide corresponding to Human GCKR aa 1-100 conjugated to keyhole limpet haemocyanin.
    (Peptide available as ab97365)

  • Positive control

    • This antibody gave a positive signal in Human liver tissue lysate.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituent: PBS

    Batches of this product that have a concentration
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Signal Transduction
    • Metabolism
    • Energy Metabolism
    • Cardiovascular
    • Atherosclerosis
    • Diabetes associated
    • Cancer
    • Cancer Metabolism
    • Metabolic signaling pathway
    • Metabolism of carbohydrates
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Carbohydrate metabolism
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Energy transfer pathways
    • Energy Metabolism
    • Metabolism
    • Types of disease
    • Diabetes
    • Metabolism
    • Types of disease
    • Cancer
    • Metabolism
    • Types of disease
    • Heart disease
    • Metabolism
    • Types of disease
    • Metabolic disorders

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
  • Recombinant Protein

    • Recombinant Human GCKR protein (Tagged) (ab225652)

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab87739 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Guaranteed

Tested applications are guaranteed to work and covered by our Abpromise guarantee.

Predicted

Predicted to work for this combination of applications and species but not guaranteed.

Incompatible

Does not work for this combination of applications and species.

Application Species
WB
Human
Application Abreviews Notes
WB
Use a concentration of 1 µg/ml. Detects a band of approximately 68 kDa (predicted molecular weight: 68 kDa).
Notes
WB
Use a concentration of 1 µg/ml. Detects a band of approximately 68 kDa (predicted molecular weight: 68 kDa).

Target

  • Function

    Inhibits glucokinase by forming an inactive complex with this enzyme.
  • Tissue specificity

    Found in liver and pancreas. Not detected in muscle, brain, heart, thymus, intestine, uterus, adipose tissue, kidney, adrenal, lung or spleen.
  • Sequence similarities

    Belongs to the GCKR family.
    Contains 2 SIS domains.
  • Target information above from: UniProt accession Q14397 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 2646 Human
    • Omim: 600842 Human
    • SwissProt: Q14397 Human
    • Unigene: 89771 Human
    • Alternative names

      • FGQTL5 antibody
      • GCK antibody
      • GCKR antibody
      • GCKR_HUMAN antibody
      • GKRP antibody
      • GLRE antibody
      • glucokinase (hexokinase 4) regulator antibody
      • Glucokinase antibody
      • Glucokinase regulator antibody
      • Glucokinase regulatory protein antibody
      • Hexokinase 4 regulator antibody
      • Hexokinase type IV antibody
      • Hexokinase-4 antibody
      • Hexokinase-D antibody
      • HK IV antibody
      • HK4 antibody
      • OTTHUMP00000158533 antibody
      see all

    Images

    • Western blot - Anti-GCKR antibody (ab87739)
      Western blot - Anti-GCKR antibody (ab87739)
      Anti-GCKR antibody (ab87739) at 1 µg/ml + Human liver tissue lysate - total protein (ab29889) at 10 µg

      Secondary
      Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

      Developed using the ECL technique.

      Performed under reducing conditions.

      Predicted band size: 68 kDa
      Observed band size: 68 kDa
      Additional bands at: 29 kDa. We are unsure as to the identity of these extra bands.


      Exposure time: 8 minutes

    Protocols

    • Western blot protocols

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab87739? Please let us know so that we can cite the reference in this datasheet.

    ab87739 has not yet been referenced specifically in any publications.

    Images

    • Western blot - Anti-GCKR antibody (ab87739)
      Western blot - Anti-GCKR antibody (ab87739)
      Anti-GCKR antibody (ab87739) at 1 µg/ml + Human liver tissue lysate - total protein (ab29889) at 10 µg

      Secondary
      Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

      Developed using the ECL technique.

      Performed under reducing conditions.

      Predicted band size: 68 kDa
      Observed band size: 68 kDa
      Additional bands at: 29 kDa. We are unsure as to the identity of these extra bands.


      Exposure time: 8 minutes

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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