Antibodies, Proteins, Kits and Reagents for Life Science

311 587 ₸ Product size

100 µg 311 587 ₸

Order now and get it on Thursday February 25, 2021

Key features and details

Product name

Anti-Gata6 antibody
See all Gata6 primary antibodies
Description

Rabbit polyclonal to Gata6
Host species

Rabbit
Tested Applications & Species

Application Species
WB
Mouse

See all applications and species data
Immunogen

Synthetic peptide corresponding to Human Gata6 aa 400 to the C-terminus conjugated to keyhole limpet haemocyanin.
(Peptide available as ab24410, ab24411)

Form

Liquid
Storage instructions

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage buffer

pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS

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Purity

Immunogen affinity purified
Clonality

Polyclonal
Isotype

IgG
Research areas

Our Abpromise guarantee covers the use of ab22600 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Guaranteed

Tested applications are guaranteed to work and covered by our Abpromise guarantee.

Predicted

Predicted to work for this combination of applications and species but not guaranteed.

Incompatible

Does not work for this combination of applications and species.

Application	Species
WB	Mouse
All applications	Rat Chicken Cow Human Pig

Application	Abreviews	Notes
WB	(2)	Use a concentration of 1 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa). Abcam recommends using milk as the blocking agent.

Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa). Abcam recommends using milk as the blocking agent.

Function

Thought to be important for regulating terminal differentiation and/or proliferation.
Tissue specificity

Expressed in heart, gut and gut-derived tissues.
Sequence similarities

Contains 2 GATA-type zinc fingers.
Domain

The GATA-type zinc fingers mediate interaction with LMCD1.
Cellular localization

Nucleus.
Target information above from: UniProt accession Q92908 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
Database links
- Entrez Gene: 2627 Human
- Entrez Gene: 14465 Mouse
- Entrez Gene: 397600 Pig
- Entrez Gene: 29300 Rat
- Omim: 601656 Human
- SwissProt: P43693 Chicken
- SwissProt: Q92908 Human
- SwissProt: Q61169 Mouse
- SwissProt: Q95JA5 Pig
- SwissProt: P46153 Rat
- Unigene: 514746 Human
- Unigene: 329287 Mouse
- Unigene: 8701 Rat
see all
Alternative names
- Gata binding factor 6 antibody
- Gata binding protein 6 antibody
- GATA-binding factor 6 antibody
- Gata6 antibody
- GATA6_HUMAN antibody
- Transcription factor Gata 6 antibody
- Transcription factor GATA-6 antibody
see all

Publishing research using ab22600? Please let us know so that we can cite the reference in this datasheet.

ab22600 has been referenced in 23 publications.

Cao Y et al. HYDIN loss-of-function inhibits GATA4 expression and enhances atrial septal defect risk. Mech Dev 162:103611 (2020). PubMed: 32376282
Li Y et al. Derivation of porcine extraembryonic endoderm-like cells from blastocysts. Cell Prolif 53:e12782 (2020). PubMed: 32196806
Canizo JR et al. A dose-dependent response to MEK inhibition determines hypoblast fate in bovine embryos. BMC Dev Biol 19:13 (2019). PubMed: 31272387
Benchetrit H et al. Direct Induction of the Three Pre-implantation Blastocyst Cell Types from Fibroblasts. Cell Stem Cell 24:983-994.e7 (2019). PubMed: 31031139
Zhang X et al. A novel chemically defined serum- and feeder-free medium for undifferentiated growth of porcine pluripotent stem cells. J Cell Physiol N/A:N/A (2019). PubMed: 30701540