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Epigenetics and Nuclear Signaling DNA / RNA DNA / Nucleotides

Anti-ds DNA antibody [rDSD/4565] (ab273137)

Anti-ds DNA antibody [rDSD/4565] (ab273137)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
  • Mouse monoclonal [rDSD/4565] to ds DNA
  • Suitable for: IHC-P
  • Reacts with: Human

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Overview

  • Product name

    Anti-ds DNA antibody [rDSD/4565]
    See all ds DNA primary antibodies
  • Description

    Mouse monoclonal [rDSD/4565] to ds DNA
  • Host species

    Mouse
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Tissue, cells or virus corresponding to ds DNA. Nuclei of Burkitt's cells

  • Positive control

    • IHC-P: Human lymph node and colon tissue; IF: MCF7 cells.
  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.

    One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.

    Learn more here.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.2
    Preservative: 0.05% Sodium azide
    Constituents: PBS, 0.05% BSA
  • Concentration information loading...
  • Purification notes

    Ab purified from Bioreactor Concentrate.
  • Clonality

    Monoclonal
  • Clone number

    rDSD/4565
  • Isotype

    IgG2a
  • Light chain type

    kappa
  • Research areas

    • Epigenetics and Nuclear Signaling
    • DNA / RNA
    • DNA / Nucleotides

Images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ds DNA antibody [rDSD/4565] (ab273137)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ds DNA antibody [rDSD/4565] (ab273137)

    Paraffin embedded human lymph node tissue stained for double stranded DNA (dsDNA) using ab273137 at 2 µg/ml in immunohistochemical analysis.

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ds DNA antibody [rDSD/4565] (ab273137)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ds DNA antibody [rDSD/4565] (ab273137)

    Immunofluorescence analysis of PFA-fixed MCF7 (human breast adenocarcinoma cell line) whole cell lysate labeling double stranded DNA (dsDNA) with ab273137 at 2 µg/ml, followed by goat anti-rabbit IgG-CF488 (green); phalloidin counterstain (red).

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ds DNA antibody [rDSD/4565] (ab273137)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ds DNA antibody [rDSD/4565] (ab273137)

    Paraffin embedded human colon tissue stained for double stranded DNA (dsDNA) using ab273137 at 2 µg/ml in immunohistochemical analysis.

  • Anti-ds DNA antibody [rDSD/4565] (ab273137)
    Anti-ds DNA antibody [rDSD/4565] (ab273137)

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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