Anti-DCDC2/RU2 antibody (ab126539)
Key features and details
- Rabbit polyclonal to DCDC2/RU2
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-DCDC2/RU2 antibody
See all DCDC2/RU2 primary antibodies -
Description
Rabbit polyclonal to DCDC2/RU2 -
Host species
Rabbit -
Tested Applications & Species
See all applications and species dataApplication Species WB Mouse
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Immunogen
Synthetic peptide corresponding to Mouse DCDC2/RU2 aa 200-300 conjugated to keyhole limpet haemocyanin.
Database link: Q5DU00 -
Positive control
- This antibody gave a positive signal in the following Mouse tissue lysates: Brain (1 day old); Cortex (3 month old); Skeletal Muscle (post natal, 0 day old); Skeletal Muscle (Embryonic, day 18); Placenta.
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General notes
This product was previously labelled as DCDC2
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration
Concentration information loading...Purity
Immunogen affinity purifiedClonality
PolyclonalIsotype
IgGResearch areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab126539 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
GuaranteedTested applications are guaranteed to work and covered by our Abpromise guarantee.
PredictedPredicted to work for this combination of applications and species but not guaranteed.
IncompatibleDoes not work for this combination of applications and species.
Application Species WB MouseAll applications RatRabbitHorseHumanPigChimpanzeeMacaque monkeyGorillaOrangutanApplication Abreviews Notes WB Use at an assay dependent concentration. Predicted molecular weight: 52 kDa.Notes WB
Use at an assay dependent concentration. Predicted molecular weight: 52 kDa.Target
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Function
May be involved in neuronal migration during development of the cerebral neocortex. -
Tissue specificity
Ubiquitously expressed. In brain, highly expressed in the entorhinal cortex, inferior temporal cortex, medial temporal cortex, hypothalamus, amygdala and hippocampus. -
Involvement in disease
Defects in DCDC2 may be a cause of susceptibility to dyslexia type 2 (DYX2) [MIM:600202]; also known as specific reading disability type 2. Dyslexia is a relatively common, complex cognitive disorder that affects 5% to 10% of school-aged children. The disorder is characterized by an impairment of reading performance despite adequate motivational, educational and intellectual opportunities and in the absence of sensory or neurological disability. -
Sequence similarities
Contains 2 doublecortin domains. - Information by UniProt
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Database links
- Entrez Gene: 51473 Human
- Entrez Gene: 195208 Mouse
- Entrez Gene: 291130 Rat
- Omim: 605755 Human
- SwissProt: Q9UHG0 Human
- SwissProt: Q5DU00 Mouse
- SwissProt: D3ZR10 Rat
- Unigene: 61345 Human
see all -
Alternative names
- DCDC 2 antibody
- DCDC2 antibody
- DCDC2_HUMAN antibody
see all
Images
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Western blot - Anti-DCDC2/RU2 antibody (ab126539)All lanes : Anti-DCDC2/RU2 antibody (ab126539) at 1/100 dilution
Lane 1 : Mouse Brain (1 day old)
Lane 2 : Mouse Cortex (3 month old)
Lane 3 : Mouse Skeletal Muscle (Post natal, 0 day old)
Lane 4 : Mouse Skeletal Muscle (Embryonic, day 18)
Lane 5 : Mouse Placenta
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 52 kDa
Observed band size: 52 kDa
Datasheets and documents
References (0)
ab126539 has not yet been referenced specifically in any publications.
Images
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Western blot - Anti-DCDC2/RU2 antibody (ab126539)All lanes : Anti-DCDC2/RU2 antibody (ab126539) at 1/100 dilution
Lane 1 : Mouse Brain (1 day old)
Lane 2 : Mouse Cortex (3 month old)
Lane 3 : Mouse Skeletal Muscle (Post natal, 0 day old)
Lane 4 : Mouse Skeletal Muscle (Embryonic, day 18)
Lane 5 : Mouse Placenta
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 52 kDa
Observed band size: 52 kDa
