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Immunology Innate Immunity Macrophage / Inflamm.

Anti-C Reactive Protein antibody (ab78051)

Price and availability

274 732 ₸

Availability

Order now and get it on Tuesday March 09, 2021

Anti-C Reactive Protein antibody (ab78051)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Rabbit polyclonal to C Reactive Protein
  • Suitable for: WB
  • Reacts with: Human
  • Isotype: IgG

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Overview

  • Product name

    Anti-C Reactive Protein antibody
    See all C Reactive Protein primary antibodies
  • Description

    Rabbit polyclonal to C Reactive Protein
  • Host species

    Rabbit
  • Tested Applications & Species

    Application Species
    WB
    Human
    See all applications and species data
  • Immunogen

    Synthetic peptide corresponding to C Reactive Protein aa 1-100 (internal sequence) conjugated to keyhole limpet haemocyanin.
    (Peptide available as ab87261)

  • Positive control

    • This antibody gave a positive signal in Human Total Plasma Protein.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituent: PBS

    Batches of this product that have a concentration
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Immunology
    • Innate Immunity
    • Macrophage / Inflamm.
    • Cardiovascular
    • Blood
    • Acute Phase Reactants
    • Immunology
    • Innate Immunity
    • Complement
    • Classical Pathway
    • Epigenetics and Nuclear Signaling
    • Chromatin Binding Proteins
    • DNA / RNA binding
    • Cardiovascular
    • Atherosclerosis
    • Vascular Inflammation
    • Inflammatory mediators
    • Cardiovascular
    • Heart
    • Apoptosis
    • Metabolism
    • Types of disease
    • Metabolic disorders

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
  • Recombinant Protein

    • Recombinant Human C Reactive Protein (ab167710)

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab78051 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Guaranteed

Tested applications are guaranteed to work and covered by our Abpromise guarantee.

Predicted

Predicted to work for this combination of applications and species but not guaranteed.

Incompatible

Does not work for this combination of applications and species.

Application Species
WB
Human
All applications
Mouse
Application Abreviews Notes
WB
Use a concentration of 1 µg/ml. Detects a band of approximately 25 kDa (predicted molecular weight: 25 kDa).
Notes
WB
Use a concentration of 1 µg/ml. Detects a band of approximately 25 kDa (predicted molecular weight: 25 kDa).

Target

  • Function

    Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
  • Tissue specificity

    Found in plasma.
  • Sequence similarities

    Belongs to the pentaxin family.
    Contains 1 pentaxin domain.
  • Cellular localization

    Secreted.
  • Target information above from: UniProt accession P02741 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 1401 Human
    • Entrez Gene: 12944 Mouse
    • Omim: 123260 Human
    • SwissProt: P02741 Human
    • SwissProt: P14847 Mouse
    • Unigene: 709456 Human
    • Unigene: 76452 Human
    • Unigene: 28767 Mouse
    • Alternative names

      • Pentraxin 1, short antibody
      • C reactive protein antibody
      • C reactive protein pentraxin related antibody
      • C-reactive protein(1-205) antibody
      • CRP antibody
      • CRP_HUMAN antibody
      • MGC88244 antibody
      • Pentraxin 1 antibody
      • PTX 1 antibody
      • PTX1 antibody
      see all

    Images

    • Western blot - Anti-C Reactive Protein antibody (ab78051)
      Western blot - Anti-C Reactive Protein antibody (ab78051)
      Anti-C Reactive Protein antibody (ab78051) at 1 µg/ml + Human Plasma Total Protein Lysate at 10 µg

      Secondary
      Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

      Developed using the ECL technique.

      Performed under reducing conditions.

      Predicted band size: 25 kDa
      Observed band size: 28 kDa
      why is the actual band size different from the predicted?
      Additional bands at: 25 kDa (possible cleavage fragment)



      We hypothesize that the 28 and 25 kDa bands represent the proform and mature form of C Reactive Protein, respectively.
    • Western blot - Anti-C Reactive Protein antibody (ab78051)
      Western blot - Anti-C Reactive Protein antibody (ab78051)

    Protocols

    • Western blot protocols

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab78051? Please let us know so that we can cite the reference in this datasheet.

    ab78051 has not yet been referenced specifically in any publications.

    Images

    • Western blot - Anti-C Reactive Protein antibody (ab78051)
      Western blot - Anti-C Reactive Protein antibody (ab78051)
      Anti-C Reactive Protein antibody (ab78051) at 1 µg/ml + Human Plasma Total Protein Lysate at 10 µg

      Secondary
      Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

      Developed using the ECL technique.

      Performed under reducing conditions.

      Predicted band size: 25 kDa
      Observed band size: 28 kDa
      why is the actual band size different from the predicted?
      Additional bands at: 25 kDa (possible cleavage fragment)



      We hypothesize that the 28 and 25 kDa bands represent the proform and mature form of C Reactive Protein, respectively.
    • Western blot - Anti-C Reactive Protein antibody (ab78051)
      Western blot - Anti-C Reactive Protein antibody (ab78051)

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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