Amoxapine, D2 and 5-HT2 receptor antagonist (ab142481)
Key features and details
- Norepinephrine and serotonin reuptake inhibitor. D2 and 5-HT2 receptor antagonist.
- CAS Number: 14028-44-5
- Purity: > 98%
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
Amoxapine, D2 and 5-HT2 receptor antagonist -
Description
Norepinephrine and serotonin reuptake inhibitor. D2 and 5-HT2 receptor antagonist. -
Biological description
Norepinephrine and serotonin reuptake inhibitor. D2 and 5-HT2 receptor antagonist. Inhibits rectifier outward K+ currents via a cAMP/PKA-dependent pathway (IC50 = 211.36 μM). Antipsychotic and antidepressant effects in vivo. Orally active. -
Purity
> 98% -
CAS Number
14028-44-5 -
Chemical structure
Properties
-
Chemical name
8-Chloro-6-piperazin-1-ylbenzo[b][1,4]benzoxazepine -
Molecular weight
313.78 -
Molecular formula
C17H16ClN3O -
PubChem identifier
2159 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
C1CN(CCN1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl -
Source
Synthetic
-
Research areas