Ambenonium chloride, acetylcholinesterase (AChE) inhibitor (ab145994)
Key features and details
- Potent, selective, reversible acetylcholinesterase (AChE) inhibitor
- CAS Number: 115-79-7
- Purity: > 98%
- Soluble in water
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Ambenonium chloride, acetylcholinesterase (AChE) inhibitor -
Description
Potent, selective, reversible acetylcholinesterase (AChE) inhibitor -
Alternative names
- Ambestigmin chloride
- Misuran
- Mytelase
- N,N'-[(1,2-Dioxo-1,2-ethanediyl)bis(imino-2,1-ethanediyl)]bis(2-chloro-N,N-diethylbenzenemethaminium) dichloride
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Biological description
Extremely potent, selective and rapidly reversible acetylcholinesterase (AChE) inhibitor (IC50 values are 0.0007 and 7 μM at AChE and BChE respectively). Used in the management of myasthenia gravis.
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Purity
> 98% -
CAS Number
115-79-7 -
Chemical structure
Properties
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Chemical name
N,N'-[(1,2-Dioxo-1,2-ethanediyl)bis(imino-2,1-ethanediyl)]bis[2-chloro-N,N-diethylbenzenemethanaminium] dichloride -
Molecular weight
608.47 -
Molecular formula
C28H42Cl4N4O2 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
