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Alloswitch-1, mGlu5 modulator (ab147022)

Key features and details

  • Photoswitchable allosteric mGlu5 modulator
  • Purity: > 98%
  • Soluble in ethanol to 10 mM and in DMSO to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Alloswitch-1, mGlu5 modulator
  • Description

    Photoswitchable allosteric mGlu5 modulator
  • Alternative names

    • Trans-alloswitch-1
  • Biological description

    Photoswitchable allosteric modulator selective for the metabotropic glutamate receptor mGlu5. Acts as a potent NAM (negative allosteric modulator) in dark or under green light but loses its NAM potency under violet light when photoisomerized.

  • Purity

    > 98%
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-chloro-N-[2-methoxy-4-(pyridin-2-yldiazenyl)phenyl]benzamide
  • Molecular weight

    366.80
  • Molecular formula

    C19H15ClN4O2
  • PubChem identifier

    76853680
  • Storage instructions

    Shipped at Room Temperature. Store at -20°C. Store In the Dark. Store under desiccating conditions.
  • Solubility overview

    Soluble in ethanol to 10 mM and in DMSO to 100 mM
  • SMILES

    Clc1ccccc1C(=O)Nc3ccc(/N=N/c2ccccn2)cc3OC
  • Source

    Synthetic

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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