Alloswitch-1, mGlu5 modulator (ab147022)
Key features and details
- Photoswitchable allosteric mGlu5 modulator
- Purity: > 98%
- Soluble in ethanol to 10 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
Alloswitch-1, mGlu5 modulator -
Description
Photoswitchable allosteric mGlu5 modulator -
Alternative names
- Trans-alloswitch-1
-
Biological description
Photoswitchable allosteric modulator selective for the metabotropic glutamate receptor mGlu5. Acts as a potent NAM (negative allosteric modulator) in dark or under green light but loses its NAM potency under violet light when photoisomerized.
-
Purity
> 98% -
Chemical structure
Properties
-
Chemical name
2-chloro-N-[2-methoxy-4-(pyridin-2-yldiazenyl)phenyl]benzamide -
Molecular weight
366.80 -
Molecular formula
C19H15ClN4O2 -
PubChem identifier
76853680 -
Storage instructions
Shipped at Room Temperature. Store at -20°C. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in ethanol to 10 mM and in DMSO to 100 mM -
SMILES
Clc1ccccc1C(=O)Nc3ccc(/N=N/c2ccccn2)cc3OC -
Source
Synthetic