AF-DX 384, M2/M4 antagonist (ab120146)
Key features and details
- M2/M4 antagonist
- CAS Number: 118290-27-0
- Purity: > 95%
- Soluble in DMSO to 50 mM and in ethanol to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
AF-DX 384, M2/M4 antagonist -
Description
M2/M4 antagonist -
Biological description
M2/M4 receptor antagonist (Kd values are 1 (M2), 2.2 (M4), 15 (M3) and 55 nM (M1)). Low blood-brain barrier permeability.
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Purity
> 95% -
CAS Number
118290-27-0 -
Chemical structure
Properties
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Chemical name
N-[2-[2-[(Dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide -
Molecular weight
478.64 -
Molecular formula
C27H38N6O2 -
PubChem identifier
119357 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM and in ethanol to 10 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C3Nc1cccnc1N(c2ccccc23)C(=O)NCCN4CCCCC4CN(CCC)CCC -
Source
Synthetic
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Research areas