A771726 (Teriflunomide), Active metabolite of leflunomide. Dihydroorotate dehydrogenase inhibitor. (ab141480)
Key features and details
- Active metabolite of leflunomide. Dihydroorotate dehydrogenase inhibitor.
- CAS Number: 108605-62-5
- Purity: > 98%
- Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
A771726 (Teriflunomide), Active metabolite of leflunomide. Dihydroorotate dehydrogenase inhibitor. -
Description
Active metabolite of leflunomide. Dihydroorotate dehydrogenase inhibitor. -
Alternative names
- Teriflunomide
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Biological description
Active metabolite of leflunomide. Inhibits dihydroorotate dehydrogenase. Shows antiproliferative effects. Active in vivo. -
Purity
> 98% -
CAS Number
108605-62-5 -
Chemical structure
Properties
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Chemical name
(Z)-2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide -
Molecular weight
270.21 -
Molecular formula
C12H9F3N2O2 -
PubChem identifier
54684141 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(=C(C#N)C(=O)NC1=CC=C(C=C1)C(F)(F)F)O -
Source
Synthetic
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Research areas
