8-Azaguanine, purine analogue with antineoplastic activity (ab145798)
Key features and details
- Purine analogue with potential antineoplastic activity. Competes with guanine in metabolism.
- CAS Number: 134-58-7
- Purity: > 99%
Soluble in DMSO to 25 mM (lot-dependent)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
8-Azaguanine, purine analogue with antineoplastic activity -
Description
Purine analogue with potential antineoplastic activity. Competes with guanine in metabolism. -
Alternative names
- 2-Amino-6-hydroxy-8-azapurine
- 2-Amino-6-oxy-8-azapurine
- 7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one, 5-amino-3,6-dihydro-
see all -
Biological description
Purine analogue with potential antineoplastic activity. Antimetabolite. Competes with guanine. Incorporated into ribonucleic acids, interfering with normal biosynthetic pathways, thus inhibiting cellular growth. Has been used in the treatment of acute leukemia.
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Purity
> 99% -
CAS Number
134-58-7 -
Chemical structure
Properties
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Chemical name
5-Amino-3,6-dihydro-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one
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Molecular weight
152.11 -
Molecular formula
C4H4N6O -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM (lot-dependent)
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Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
