4-Bromo A23187, nonfluorescent Ca2+ ionophore (ab142244)
Key features and details
- Highly selective, nonfluorescent Ca2+ ionophore
- CAS Number: 76455-82-8
- Purity: > 98%
- Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
4-Bromo A23187, nonfluorescent Ca2+ ionophore -
Description
Highly selective, nonfluorescent Ca2+ ionophore -
Biological description
Highly selective, nonfluorescent Ca2+ ionophore. Halogenated analogue of A23187 (Asc 287). Increases intracellular Ca2+. Active in vivo. -
Purity
> 98% -
CAS Number
76455-82-8 -
Chemical structure
Properties
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Chemical name
6-Bromo-5-(methylamino)-2-[[3,5,9-trimethyl-2-[1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-8-yl]methyl]-1,3-benzoxazole-4-carboxylic acid -
Molecular weight
602.52 -
Molecular formula
C29H36BrN3O6 -
PubChem identifier
5047377 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1CCC2(C(CC(C(O2)C(C)C(=O)C3=CC=CN3)C)C)OC1CC4=NC5=C(C(=C(C=C5O4)Br)NC)C(=O)O -
Source
Synthetic
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Research areas