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Biochemicals

4-Bromo A23187, nonfluorescent Ca2+ ionophore (ab142244)

Key features and details

  • Highly selective, nonfluorescent Ca2+ ionophore
  • CAS Number: 76455-82-8
  • Purity: > 98%
  • Soluble in DMSO
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    4-Bromo A23187, nonfluorescent Ca2+ ionophore
  • Description

    Highly selective, nonfluorescent Ca2+ ionophore
  • Biological description

    Highly selective, nonfluorescent Ca2+ ionophore. Halogenated analogue of A23187 (Asc 287). Increases intracellular Ca2+. Active in vivo.
  • Purity

    > 98%
  • CAS Number

    76455-82-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    6-Bromo-5-(methylamino)-2-[[3,5,9-trimethyl-2-[1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-8-yl]methyl]-1,3-benzoxazole-4-carboxylic acid
  • Molecular weight

    602.52
  • Molecular formula

    C29H36BrN3O6
  • PubChem identifier

    5047377
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1CCC2(C(CC(C(O2)C(C)C(=O)C3=CC=CN3)C)C)OC1CC4=NC5=C(C(=C(C=C5O4)Br)NC)C(=O)O
  • Source

    Synthetic

  • Research areas

    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Ion Channels
    • Ionophores, Indicators & Chelators
    • Biochemicals
    • Pharmacology
    • Signaling
    • Ca2+ signaling
    • Ionophores, Indicators & Chelators
    • Biochemicals
    • Chemical Type
    • Dyes, stains and fluorescent tools

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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