3-Deazaneplanocin A (ab142215)
Key features and details
- Potent S-adenosylhomocysteine hydrolase (SAHH) and histone methyltransferase (HMT) inhibitor
- CAS Number: 102052-95-9
- Purity: > 98%
- Soluble in DMSO to 75 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
3-Deazaneplanocin A -
Description
Potent S-adenosylhomocysteine hydrolase (SAHH) and histone methyltransferase (HMT) inhibitor -
Biological description
Potent S-adenosylhomocysteine hydrolase (SAHH) and histone methyltransferase (HMT) inhibitor. Anticancer agent. Induces apoptosis in cancer cells but not in normal cells. Active in vivo. -
Purity
> 98% -
CAS Number
102052-95-9 -
Chemical structure
Properties
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Chemical name
(1S,2R,5R)-5-(4-Aminoimidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol -
Molecular weight
262.26 -
Molecular formula
C12H14N4O3 -
PubChem identifier
73087 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 75 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CN=C(C2=C1N(C=N2)C3C=C(C(C3O)O)CO)N -
Source
Synthetic
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Research areas
